Sharon Collins Presnell, PhD
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Dr. Presnell has more than 16 years of experience in the leadership of product-focused R&D. As an assistant professor at the University of North Carolina at Chapel Hill, Dr. Presnell’s research in liver and prostate biology and carcinogenesis produced cell- and tissue-based technologies that were industry-funded or outlicensed for industrial applications. She joined Becton Dickinson (BD) in 2001 and played a key role in the early discovery and development of cell-based tools and reagents for BD’s life sciences portfolio. At BD, she grew and led a large multi-disciplinary team to build and validate screening platforms and products for cell growth, differentiation, and characterization and secured revenue-generating commercial partnerships with pharma partners. Sharon joined Tengion, Inc. in 2007, and as the Senior Vice President of Regenerative Medicine Research, was responsible for leading the discovery and early development of Tengion’s Neo-Kidney Augment™, a clinical-stage cell-based therapy for patients with chronic kidney disease. As the Chief Technology Officer at Organovo, Dr. Presnell has led the growth and development of the R&D organization, including evolution of the company’s technology portfolio, and has played an instrumental role in securing funds in support of corporate growth initiatives. Sharon holds a PhD in pathology from the Medical College of Virginia. Dr. Presnell is a member of the American Society of Investigative Pathology, the American Society of Nephrology, and the International Society of Cell Transplantation, serves on the editorial board of the journal ‘3D Printing and Additive Manufacturing’, and remains active as an NIH reviewer as an industry representative in the biomedical engineering space.
Jennifer Kinsbruner Bush, JD
General Counsel, Corporate Secretary and Compliance Officer
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Ms. Bush has more than 15 years of intellectual property, corporate legal, regulatory, compliance, and transactional experience. Prior to joining Organovo, Ms. Bush held positions of increasing responsibility at Broadcom Corp., where she was most recently Associate General Counsel. Before joining Broadcom, Ms. Bush served as Associate General Counsel of DivX, Inc. prior to its acquisition by Sonic Solutions in October 2010. Earlier in her career, Ms. Bush was a Principal at Fish & Richardson, from 2001 to January 2010 where she represented clients focused on a variety of technologies, including in the areas of medical devices, life sciences, software, and consumer products. Ms. Bush received a J.D. from Yale Law School and an A.B. in history and Latin American Studies from Princeton University.
Associate Director of Lab Operations
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Mr. Dorko is the Associate Director of Laboratory Operations at Samsara Sciences Inc. Ken received his B.S. degree from the University of Pittsburgh in 1989. Prior to his current position, Mr. Dorko worked in multiple technical positions at the University of Pittsburgh and the University of Kansas Medical Center. He was trained to perform human hepatocyte isolations at the University of Pittsburgh Department of Surgery by Dr. Andreas Nussler. In 1994 he joined the laboratory of Dr. Stephen Strom and was involved in the isolation of hepatocytes from over 1,800 human livers. Mr. Dorko was also a key contributor in developing the first FDA approved laboratory for clinical hepatocyte transplantation. During his time in Dr. Strom’s laboratory Mr. Dorko also managed the distribution of human hepatocytes to other investigators nationwide through the NIH funded Liver Tissue and Cell Distribution System (LTCDS). In 2012 Mr. Dorko joined the Department of Pharmacology, Toxicology and Therapeutics at the University of Kansas Medical Center to become the Technical Director of the Bio-specimen Core Laboratory (later renamed the Cell Isolation Core Laboratory) and to establish a cell isolation core laboratory. The Cell Isolation Core Laboratory was a NIH/COBRE funded lab that specialized in the isolation of human and rodent liver cells for investigator research. Mr. Dorko is an expert in human hepatocyte isolation, is a member of the Cell Transplant Society and has over 40 peer reviewed publications and book chapters.